In a modern business there are two things that really matter: correctly maintaining/managing data and staying agile in a rapidly changing environment. At the meeting-point between these two trends, we witness an ongoing war between traditional data management tools (like MS Excel or MS Access) and recent solutions (like custom online databases). I suggest: turn enemies into friends - convert Excel to a database online and make business, not war.
A Second Nature
Excel has been around for more than 30 years now, and data management technologies have developed greatly since than There have been a whole bunch of heavy hitters trying to dethrone the spreadsheet giant. And yes, sometimes Excel is just a pit of frustration. Piling errors in spreadsheets, troublesome information sharing, and problematic concurrent access by multiple users are Excel's biggest drawbacks.